Structure of PDB 6bxz Chain C Binding Site BS01

Receptor Information

>6bxz Chain C (length=334) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GEIPRFTQEEYRPPPVSELAAKGTMVGLISAAAINQSIVYSIVSGNEEDK
FGINNITGVIYVNAPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAK
VYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDKDTGNYSAM
AYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYG
KGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIEDLTEILDRYVQEQI
PGAKVVVESIGARRHGDAFSLEDYTKCDLTVYAIDPQTNRAVDRNELFKF
LDGKLLDINKDFQPYYGEGGRILEIRTPEAVTSI

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

6bxz Chain C Residue 1401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6bxz A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15.
Resolution	2.09 Å
Binding residue (original residue number in PDB)	E1026 D1075 E1077 D1118
Binding residue (residue number reindexed from 1)	E18 D67 E69 D110
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609	cell-cell adhesion

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:6bxz, PDBe:6bxz, PDBj:6bxz
PDBsum	6bxz
PubMed	30527337
UniProt	F1SD06

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