Structure of PDB 6bjy Chain C Binding Site BS01

Receptor Information
>6bjy Chain C (length=413) Species: 11285 (Vesicular stomatitis Indiana virus strain San Juan) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDL
RGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDT
IGIFDLVSLKALDGVLPDGVSDASRTSADDKWLPLYLLGLYRVGRTQMPE
YRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMF
FHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILN
REVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWG
QLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVG
DNKYTPTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLRE
KTIGKYAKSEFDK
Ligand information
>6bjy Chain R (length=45) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuu
.............................................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6bjy A Polyamide Inhibits Replication of Vesicular Stomatitis Virus by Targeting RNA in the Nucleocapsid.
Resolution3.46 Å
Binding residue
(original residue number in PDB)		R143 R146 M149 E151 K155 Y215 D224 S285 K286 S287 S290 S291 V292 R312 N315 R317 R408
Binding residue
(residue number reindexed from 1)		R142 R145 M148 E150 K154 Y214 D223 S284 K285 S286 S289 S290 V291 R311 N314 R316 R399
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0019083 viral transcription
GO:0039703 RNA replication
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6bjy, PDBe:6bjy, PDBj:6bjy
PDBsum6bjy
PubMed29437970
UniProtP03521|NCAP_VSIVA Nucleoprotein (Gene Name=N)

[Back to BioLiP]