Structure of PDB 6bgs Chain C Binding Site BS01

Receptor Information
>6bgs Chain C (length=101) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYA
DKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
H
Ligand information
Receptor-Ligand Complex Structure
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PDB6bgs Modifications to a common phosphorylation network provide individualized control in caspases.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		Y204 S205 W206 R207 N208 S209 S249
Binding residue
(residue number reindexed from 1)		Y27 S28 W29 R30 N31 S32 S72
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6bgs, PDBe:6bgs, PDBj:6bgs
PDBsum6bgs
PubMed29414778
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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