Structure of PDB 6b9l Chain C Binding Site BS01
Receptor Information
>6b9l Chain C (length=174) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
KEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMYSVCNVMSGD
QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAES
DLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRK
GFYLAFQDIGACVALLSVRVYYKK
Ligand information
>6b9l Chain G (length=10) Species:
32644
(unidentified) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
SAYPDSVPFR
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6b9l
Structure-Based Design of Novel EphA2 Agonistic Agents with Nanomolar Affinity in Vitro and in Cell.
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
L54 M55 Q56 N57 M59 Y65 M66 R103 F108 F156 R159 V161 C188
Binding residue
(residue number reindexed from 1)
L28 M29 Q30 N31 M33 Y39 M40 R77 F82 F130 R133 V135 C162
Enzymatic activity
Enzyme Commision number
2.7.10.1
: receptor protein-tyrosine kinase.
External links
PDB
RCSB:6b9l
,
PDBe:6b9l
,
PDBj:6b9l
PDBsum
6b9l
PubMed
30110533
UniProt
P29317
|EPHA2_HUMAN Ephrin type-A receptor 2 (Gene Name=EPHA2)
[
Back to BioLiP
]
