Structure of PDB 6aso Chain C Binding Site BS01

Receptor Information
>6aso Chain C (length=79) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
METPLDLLKLNLDERVYIKLRGARTLVGTLQAFDSHCNIVLSDAVETIYQ
LNNEELSESERRCEMVFIRGDTVTLISTP
Ligand information
>6aso Chain I (length=70) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caauuugaaacaauacagagaugaucagcgguuccccugcauaaggggaa
ccguuuuacaaagaguuuuu
...<<<<...................<<<<<<<<<<<<.....>>>>>>>
>>>>>...>>>>........
Receptor-Ligand Complex Structure
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PDB6aso Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA.
Resolution2.71 Å
Binding residue
(original residue number in PDB)		R21 H36 N38 R69 G70 D71
Binding residue
(residue number reindexed from 1)		R21 H36 N38 R69 G70 D71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000398 mRNA splicing, via spliceosome
GO:0006364 rRNA processing
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0008380 RNA splicing
GO:0033962 P-body assembly
Cellular Component
GO:0000932 P-body
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005688 U6 snRNP
GO:0005730 nucleolus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0005737 cytoplasm
GO:0032991 protein-containing complex
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071011 precatalytic spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:1990726 Lsm1-7-Pat1 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6aso, PDBe:6aso, PDBj:6aso
PDBsum6aso
PubMed29717126
UniProtP57743|LSM3_YEAST U6 snRNA-associated Sm-like protein LSm3 (Gene Name=LSM3)

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