Structure of PDB 6asd Chain C Binding Site BS01

Receptor Information
>6asd Chain C (length=45) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKRKRCGVCEPCQQKTNCGECTYCKNRKNSHQICKKRKCEELKKK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6asd DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Resolution1.85 Å
Binding residue
(original residue number in PDB)
K587 K589 T607 Y608 H616 Q617 K620
Binding residue
(residue number reindexed from 1)
K2 K4 T22 Y23 H31 Q32 K35
Binding affinityPDBbind-CN: Kd=2.4uM
Enzymatic activity
Enzyme Commision number 1.14.11.80: methylcytosine dioxygenase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6asd, PDBe:6asd, PDBj:6asd
PDBsum6asd
PubMed29276034
UniProtQ8NFU7|TET1_HUMAN Methylcytosine dioxygenase TET1 (Gene Name=TET1)

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