Structure of PDB 5zeb Chain C Binding Site BS01

Receptor Information
>5zeb Chain C (length=273) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRKYKPTTPGRRGASVSDFAEITRSTPEKSLVRPLHGKGGRNAHGRITTR
HKGGGHKRAYRVIDFRRHDKDGVNAKVAHIEYDPNRTANIALLHYLDGEK
RYIIAPQGLKQGDVIESGANADIKPGNNLPLRNIPAGTVIHAVELRPGGG
AKLARSAGVSIQLLGKEGTYAALRMPSGEIRRVDVRCRATVGEVGNAEQS
NINWGKAGRMRWKGKRPTVRGVVMNPVDHPHGGGEGKTSGGRHPVSPWGK
PEGRTRKPNKPSDKLIVRRRRTG
Ligand information
>5zeb Chain a (length=1506) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaacac
augcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacgg
gugaguaacacgugggugaucugcccugcacuuugggauaagccugggaa
acugggucuaauaccgaauacacccugcuggucgcauggccugguagggg
aaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggugg
ggugauggccuaccaaggcgacgacggguagccggccugagagggugacc
ggccacacugggacugagauacggcccagacuccuacgggaggcagcagu
ggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcgugag
ggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgcaa
gugacgguaugugcagaagaaggaccggccaacuacgugccagcagccgc
gguaauacguaggguccgagcguuguccggaauuacugggcguaaagagc
ucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugugg
gcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaauu
ccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcga
aggcgggucucugggcaguaacugacgcugaggagcgaaagcguggggag
cgaacaggauuagauacccugguaguccacgccguaaacgguggguacua
gguguggguuuccuugggauccgugccguagcuaacgcauuaaguacccc
gccuggggaguacggccgcaaggcuaaaacucaaaggaauugacgggggc
ccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaagaacc
uuaccuggguuugacaugcacaggacgccggcagagaugucgguucccuu
guggccugugugcagguggugcauggcugucgucagcucgugucgugaga
uguuggguuaagucccgcaacgagcgcaacccuugucucauguugccagc
acguuaugguggggacucgugagagacugccggggucaacucggaggaag
guggggaugacgucaagucaucaugccccuuauguccagggcuucacaca
ugcuacaauggccgguacaaagggcugcgaugccgugagguggagcgaau
ccuuucaaagccggucucaguucggaucggggucugcaacucgaccccgu
gaagucggagucgcuaguaaucgcagaucagcaacgcugcggugaauacg
uucccgggccuuguacacaccgcccgucacgucaugaaagucgguaacac
ccgaagccgguggccuaacccuuguggagggagccgucgaaggugggauc
ggcgauugggacgaagucguaacaagguagccguaccggaaggugcggcu
ggauca
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<
.<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>......
<<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<....
..>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>>.
...<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<
<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>
>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>
>.........<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<<<
<......<<<<....>>>>.....>>>>...<.<<<<<......<<....
>>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))>>
.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<
<<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>>>
>...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....<<
<<<<<<<..<<<......>>>.....>>>>>>>>>...........<<..
..>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<
<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<..
<<<<<<<<<<<<...>>>>>>>>>>>>...<<..))>>.....>>>>>>.
>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<
<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.......
...<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.<<...
..>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>
>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....<<..<
<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>......
..>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>
>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>....
>>>......>>>>>>>......<....<<<<<<<........>>>>>>>.
...>.....>>>>>>....<<<<<<<..........>>>>>>>......>
>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<..<<<
<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>>..>>>
>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>
......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5zeb Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		L166 R176 N203
Binding residue
(residue number reindexed from 1)		L164 R174 N201
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0016740 transferase activity
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5zeb, PDBe:5zeb, PDBj:5zeb
PDBsum5zeb
PubMed30206241
UniProtA0QSD4|RL2_MYCS2 Large ribosomal subunit protein uL2 (Gene Name=rplB)

[Back to BioLiP]