Structure of PDB 5ze1 Chain C Binding Site BS01

Receptor Information
>5ze1 Chain C (length=623) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HINKGGRPRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTL
FLLALRARNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKM
YRTVKAITGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGI
IDGLSGLASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLD
DYLNGPFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHG
SQNVKVFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKS
SELTLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTR
LEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPF
IETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLD
KHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMD
LYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITN
YFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFRRFRKMNARQSKCYEM
EDVLKHHWLYTSKYLQKFMNAHN
Ligand information
>5ze1 Chain F (length=45) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgggtttttgttaagggctgtatcactgtgtaagacaggccagat
Receptor-Ligand Complex Structure
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PDB5ze1 Cracking the DNA Code for V(D)J Recombination
Resolution3.0 Å
Binding residue
(original residue number in PDB)		K388 G390 R391 R393 T400 R402 R407 Y485 K489 H501 K608 H609 Q978
Binding residue
(residue number reindexed from 1)		K4 G6 R7 R9 T16 R18 R23 Y101 K105 H117 K224 H225 Q594
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:5ze1, PDBe:5ze1, PDBj:5ze1
PDBsum5ze1
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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