Structure of PDB 5z5a Chain C Binding Site BS01

Receptor Information
>5z5a Chain C (length=147) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MWPSAKFIDGRVAFSRMPAERELDEVARDFDAVVVLVEDYELPYSLDEWE
KRGVEVLHGPIPDFTAPSVEQLLEILRWIEERVREGKKVLIHCMGGLGRS
GTVGVAWLMYSRGLSLREALMEVRRKRPGAVETQEQMEVLKELEERI
Ligand information
Ligand IDVN3
InChIInChI=1S/3O.V/q;;;-1
InChIKeyYTVPPYMZCLYRBX-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		O=[V-](=O)=O
FormulaO3 V
NameVANADATE ION;
METAVANADATE
ChEMBL
DrugBank
ZINC
PDB chain5z5a Chain C Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5z5a Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D63 C93 M94 G95 G96 L97 G98 R99
Binding residue
(residue number reindexed from 1)		D63 C93 M94 G95 G96 L97 G98 R99
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5z5a, PDBe:5z5a, PDBj:5z5a
PDBsum5z5a
PubMed29791483
UniProtQ8X270

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