Structure of PDB 5ye4 Chain C Binding Site BS01

Receptor Information
>5ye4 Chain C (length=211) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIQLVQSGPELKKPGETVKISCKASGYTFTDYSMHWVKQAPGKGLKWMGW
INTETGEPTYADDFKGRFAFSLETSATTAYLQINNLKNEDTATYFCGRDY
WGQGTTLTVSSAKTTPPSVYPLAPGCGDTTGSSVTLGCLVKGYFPESVTV
TWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSQTVTCSVAHPAS
STTVDKKLEPS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ye4 JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states.
Resolution1.799 Å
Binding residue
(original residue number in PDB)
I2 Y27 H35 R98 D99 Y100
Binding residue
(residue number reindexed from 1)
I2 Y27 H35 R98 D99 Y100
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