Structure of PDB 5x2q Chain C Binding Site BS01

Receptor Information

>5x2q Chain C (length=431) Species: 8090 (Oryzias latipes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TSEFHLRGDYLIGGLFNIHYVAAANFQRPQAIDCSSKLFILPNYRRFQMM
RFSVEEINNSSSLLPNVSLGYQMFDHCSDIHSFPGIFKLLSVNDLIRPWE
DASTGLPNAIGVVGPFTSTHALSIAPIFMTNLFPMVSYGCSGSVFSKENL
YPSFLRTVHSNKDVINAIVGIILNFNWRWVAFLYSDDDFGKDGLEQFKNK
IEDSEICLAFYKAINVNTDYLQVFKQIEEQNIKVIVVFAPKVYAEAVVES
AVQLNVTNKVWIADDGWSLNKKLPSMNGIQNIGTVLGVAQPVVTIPGFTD
FIYSAISQFCNQKCNCSNLSVKSLLNADPSFSFPVYAAVYAIAHALHNTL
RCGSDRCPKNITVHPHMILEELKKSNFTLLNQTVQFDENGDPKFGSLSVV
FWNSSGNAEEVGSYHFQSSIHLSINKTKIKW

Ligand information

Ligand ID

GLY

InChI

InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChIKey

DHMQDGOQFOQNFH-UHFFFAOYSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 1.5.0	C(C(=O)O)N
CACTVS 3.341	NCC(O)=O
ACDLabs 10.04	O=C(O)CN

Formula

C2 H5 N O2

Name

GLYCINE

PDB chain

5x2q Chain C Residue 951 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	5x2q Structural basis for perception of diverse chemical substances by T1r taste receptors
Resolution	2.6 Å
Binding residue (original residue number in PDB)	T141 S142 S165 F213
Binding residue (residue number reindexed from 1)	T117 S118 S141 F189
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004930	G protein-coupled receptor activity

	Biological Process
GO:0007186	G protein-coupled receptor signaling pathway

	Cellular Component
GO:0016020	membrane

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:5x2q, PDBe:5x2q, PDBj:5x2q
PDBsum	5x2q
PubMed	28534491
UniProt	A0A173M0G2

[Back to BioLiP]