Structure of PDB 5wxc Chain C Binding Site BS01

Receptor Information
>5wxc Chain C (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFG
CDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAA
HVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
Ligand information
>5wxc Chain F (length=7) Species: 1774282 (Influenza A virus (A/chicken/China/028/2014(H7N9))) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LYKKMTF
Receptor-Ligand Complex Structure
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PDB5wxc Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses.
Resolution2.295 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 H70 N77 I80 Y84 L95 M97 F99 Y123 T143 K146 W147 Y159 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 H70 N77 I80 Y84 L95 M97 F99 Y123 T143 K146 W147 Y159 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5wxc, PDBe:5wxc, PDBj:5wxc
PDBsum5wxc
PubMed30087171
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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