Structure of PDB 5wtb Chain C Binding Site BS01

Receptor Information
>5wtb Chain C (length=323) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NNVNDLITVTKQTIKVGDNVAAAHDGKDIEYDTEFTIDNKVKKGDTMTIN
YDKNVIPSDLTDKNDPIDITDPSGEVIAKGTFDKATKQITYTFTDYVDKY
EDIKARLTLYSYIDKQAVPNETSLNLTFATAGKETSQNVSVDYQDPMVHG
DSNIQSIFTKLDENKQTIEQQIYVNPLKKTATNTKVDIAGSQVDDYGNIK
LGNGSTIIDQNTEMKVYKVNPNQQLPQSNRIYDFSQYEDVTSQFDNKKSF
SNNVATLDFGDINSAYIIKVVSKYTPTSDGELDIAQGTSMRTTDKYGYYN
YAGYSNFIVTSNDTGGGDGTVKP
Ligand information
Receptor-Ligand Complex Structure
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PDB5wtb Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Resolution3.3 Å
Binding residue
(original residue number in PDB)		H299 D300 G301 P332 S333 D334 L335 Y387 Q419 F433 S580 N581 F582 I583 V584 T585 S586 N587
Binding residue
(residue number reindexed from 1)		H24 D25 G26 P57 S58 D59 L60 Y112 Q144 F158 S305 N306 F307 I308 V309 T310 S311 N312
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005618 cell wall

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Biological Process
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Cellular Component
External links
PDB RCSB:5wtb, PDBe:5wtb, PDBj:5wtb
PDBsum5wtb
PubMed28258151
UniProtQ932F7|SDRE_STAAM Serine-aspartate repeat-containing protein E (Gene Name=sdrE)

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