Structure of PDB 5w5r Chain C Binding Site BS01

Receptor Information
>5w5r Chain C (length=415) Species: 358 (Agrobacterium tumefaciens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VQPLARDAMAYVLAGGRGSRLKELTDRRAKPAVYFGGKARIIDFALSNAL
NSGIRRIGVATQYKAHSLIRHLQRGWDFFRPERNESFDILAASQRVSETQ
WYEGTADAVYQNIDIIEPYAPEYMVILAGDHIYKMDYEYMLQQHVDSGAD
VTIGCLEVPRMEATGFGVMHVNEKDEIIDFIEKPADPPGIPGNEGFALAS
MGIYVFHTKFLMEALRRDAADPTSSRDFGKDIIPYIVEHGKAVAHRFADS
CVRSDFEHEPYWRDVGTIDAYWQANIDLTDVVPDLDIYDKSWPIWTYAEI
TPPAKFVHDDEDRRGSAVSSVVSGDCIISGAALNRSLLFTGVRANSYSRL
ENAVVLPSVKIGRHAQLSNVVIDHGVVIPEGLIVGEDPELDAKRFRRTES
GICLITQSMIDKLDL
Ligand information
Ligand IDPYR
InChIInChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
InChIKeyLCTONWCANYUPML-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385CC(=O)C(O)=O
OpenEye OEToolkits 1.7.6CC(=O)C(=O)O
ACDLabs 12.01O=C(C(=O)O)C
FormulaC3 H4 O3
NamePYRUVIC ACID
ChEMBLCHEMBL1162144
DrugBankDB00119
ZINCZINC000001532517
PDB chain5w5r Chain I Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5w5r Structural analysis reveals a pyruvate-binding activator site in theAgrobacterium tumefaciensADP-glucose pyrophosphorylase.
Resolution1.754 Å
Binding residue
(original residue number in PDB)		K44 P309 A310 S329 G330
Binding residue
(residue number reindexed from 1)		K38 P303 A304 S323 G324
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.27: glucose-1-phosphate adenylyltransferase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008878 glucose-1-phosphate adenylyltransferase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0005978 glycogen biosynthetic process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5w5r, PDBe:5w5r, PDBj:5w5r
PDBsum5w5r
PubMed30401744
UniProtP39669|GLGC_RHIRD Glucose-1-phosphate adenylyltransferase (Gene Name=glgC)

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