Structure of PDB 5vvv Chain C Binding Site BS01
Receptor Information
>5vvv Chain C (length=423) Species:
9606
(Homo sapiens) [
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HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKSNLYSPQMALKLALTEWLQEFSVTL
EDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSIEEWRSRAAKFEEMC
GLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSS
AQFLIEPWAFRGGLAGEFQRLLP
Ligand information
>5vvv Chain B (length=2) Species:
9606
(Homo sapiens) [
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ST
Receptor-Ligand Complex Structure
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PDB
5vvv
Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
W645 W679
Binding residue
(residue number reindexed from 1)
W377 W408
Enzymatic activity
Enzyme Commision number
3.2.1.169
: protein O-GlcNAcase.
External links
PDB
RCSB:5vvv
,
PDBe:5vvv
,
PDBj:5vvv
PDBsum
5vvv
PubMed
28939839
UniProt
O60502
|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)
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