Structure of PDB 5vvu Chain C Binding Site BS01

Receptor Information
>5vvu Chain C (length=429) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKSNMLYSPQMALKLALTEWLQEFSVT
LEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVIEEWRSRAAKFE
EMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRS
HSSAQFLIGDQEPWAFRGGLAGEFQRLLP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vvu Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
F625 W679
Binding residue
(residue number reindexed from 1)
F360 W414
Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
External links
PDB RCSB:5vvu, PDBe:5vvu, PDBj:5vvu
PDBsum5vvu
PubMed28939839
UniProtO60502|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)

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