Structure of PDB 5vsu Chain C Binding Site BS01

Receptor Information
>5vsu Chain C (length=81) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSMETPLDLLKLNLDERVYIKLRGARTLVGTLQAFDSHCNIVLSDAVETI
YQLNNEELSESERRCEMVFIRGDTVTLISTP
Ligand information
>5vsu Chain I (length=73) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauuugaaacaauacagagaugaucagcgguuccccugcauaaggagaac
cguuuuacaaagagauuuguuuu
..<<<<...................<<<<<<<<.<<.......>>.>>>>
>>>>...>>>>............
Receptor-Ligand Complex Structure
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PDB5vsu Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		H36 N38 R69 G70 D71
Binding residue
(residue number reindexed from 1)		H38 N40 R71 G72 D73
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000398 mRNA splicing, via spliceosome
GO:0006364 rRNA processing
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0008380 RNA splicing
GO:0033962 P-body assembly
Cellular Component
GO:0000932 P-body
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005688 U6 snRNP
GO:0005730 nucleolus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0005737 cytoplasm
GO:0032991 protein-containing complex
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071011 precatalytic spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:1990726 Lsm1-7-Pat1 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5vsu, PDBe:5vsu, PDBj:5vsu
PDBsum5vsu
PubMed29717126
UniProtP57743|LSM3_YEAST U6 snRNA-associated Sm-like protein LSm3 (Gene Name=LSM3)

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