Structure of PDB 5v1d Chain C Binding Site BS01
Receptor Information
>5v1d Chain C (length=244) Species:
9913
(Bos taurus) [
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SLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKMIIPSLDGD
LFQWDRDRESMETVPFTVESLLEDVVLVGGKSLTTYGLSAYSGKVRYICS
ALGCRQWDDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPSDVEE
QEAVMMDTVIKVSVADWKVMAFNKKGGHLEWEYQFSTPIASAWLVKDGKV
IPISLFDDTSIVEAARGATENSVYLGMYRGQLYLQSSVRISEKF
Ligand information
>5v1d Chain F (length=9) Species:
32630
(synthetic construct) [
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PQPWRFYAP
Receptor-Ligand Complex Structure
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PDB
5v1d
The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization
Resolution
2.799 Å
Binding residue
(original residue number in PDB)
W165 M172 E173 E384 S386 V387 Y388 L389
Binding residue
(residue number reindexed from 1)
W54 M61 E62 E220 S222 V223 Y224 L225
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5v1d
,
PDBe:5v1d
,
PDBj:5v1d
PDBsum
5v1d
PubMed
29386355
UniProt
A5D791
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