Structure of PDB 5un8 Chain C Binding Site BS01
Receptor Information
>5un8 Chain C (length=429) Species:
9606
(Homo sapiens) [
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HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKSNMLYSPQMALKLALTEWLQEFSVT
LEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVIEEWRSRAAKFE
EMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRS
HSSAQFLIGDQEPWAFRGGLAGEFQRLLP
Ligand information
>5un8 Chain E (length=7) Species:
9606
(Homo sapiens) [
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WVDSTPP
Receptor-Ligand Complex Structure
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PDB
5un8
Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Resolution
2.13 Å
Binding residue
(original residue number in PDB)
M622 W645 W679
Binding residue
(residue number reindexed from 1)
M357 W380 W414
Enzymatic activity
Enzyme Commision number
3.2.1.169
: protein O-GlcNAcase.
External links
PDB
RCSB:5un8
,
PDBe:5un8
,
PDBj:5un8
PDBsum
5un8
PubMed
28319083
UniProt
O60502
|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)
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