Structure of PDB 5ulh Chain C Binding Site BS01

Receptor Information
>5ulh Chain C (length=51) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTDEKCTICLSMLEDGEDVRRLPCAHLFHQLCVDQWLAMSKKCPICRVDI
E
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5ulh Chain C Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5ulh Discovery of new non-covalent ubiquitin binding sites on UbcH5
Resolution1.95 Å
Binding residue
(original residue number in PDB)		C312 H314 C331 C334
Binding residue
(residue number reindexed from 1)		C24 H26 C43 C46
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity

View graph for
Molecular Function
External links
PDB RCSB:5ulh, PDBe:5ulh, PDBj:5ulh
PDBsum5ulh
PubMed
UniProtQ6ZSG1|ARK2C_HUMAN E3 ubiquitin-protein ligase ARK2C (Gene Name=ARK2C)

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