Structure of PDB 5tx1 Chain C Binding Site BS01

Receptor Information
>5tx1 Chain C (length=946) Species: 46928 (Human adenovirus 26) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSMMPQWAYMHIAGQDASEYLSPGLVQFARATDTYFSLGNKFRNPTVAPT
HDVTTDRSQRLTLRFVPVDREATTYLYKARFTLAVGDNRVLDMASTYFDI
RGVLDRGPSFKPYSGTAYNSLAPKGAPNPSQWETKEKQGTTGGVQQEKDV
TKTFGVAATGGINITNQGLLLGTDETAENGKKDIYADKTFQPEPQVGEEN
WQENEAFYGGRALKKDTKMKPCYGSFARPTNEKGGQAKFKPVNEGEQPKD
LDIDFAYFDVPGGSPPAGGSGEEYKADIILYTENVNLETPDTHVVYKPGT
SDNSSEINLVQQSMPNRPNYIGFRDNFVGLMYYNSTGNMGVLAGQASQLN
AVVDLQDRNTELSYQLLLDSLGDRTRYFSMWNSAVDSYDPDVRIIENHGV
EDELPNYCFPLNGTGTNSTYQGVKITNGNDGAEESEWEKDDAISRQNQIC
KGNVYAMEINLQANLWKSFLYSNVALYLPDSYKYTPANVKLPANTNTYEY
MNGRVVAPSLVDAYINIGARWSLDPMDNVNPFNHPRNAGLRYRSMLLGNG
RYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMILQSSLGNDLRV
DGASVRFDSVNLYATFFPMAHNTASTLEAMLRNDTHDQSFNDYLSAANML
YPIPAKATNVPISIPSRNWAAFRGWSFTRLKTKETPSLGSGFDPYFVYSG
SIPYLDGTFYLNHTFKKVSIMFDSSVSWPGNDRLLTPNEFEIKRSVDGEG
YNVAQCNMTKDWFLVQMLSHYNIGYQGFHVPEGYKDRMYSFFRNFQPMSR
QVVDEINYKDYKAVTLPFQHNNSGFTGYLAPTMRQGQPYPANFPYPLIGQ
TAVPSVTQKKFLCDRVMWRIPFSSNFMSMGALTDLGQNMLYANSAHALDM
TFEVDPMDEPTLLYLLFEVFDVVRVHQPHRGVIEAVYLRTPFSAGN
Ligand information
>5tx1 Chain 2 (length=27) Species: 46928 (Human adenovirus 26) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DINFASLAPRHGTRPFMGTWNEIGTSQ
Receptor-Ligand Complex Structure
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PDB5tx1 Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		S21 L24 V29 Q30 R33 A34 T35 Y38 G42 F45 R46 N47
Binding residue
(residue number reindexed from 1)		S18 L21 V26 Q27 R30 A31 T32 Y35 G39 F42 R43 N44
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5tx1, PDBe:5tx1, PDBj:5tx1
PDBsum5tx1
PubMed28508067
UniProtQ3S8B3

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