Structure of PDB 5o3u Chain C Binding Site BS01

Receptor Information
>5o3u Chain C (length=706) Species: 39387 (Gypsophila vaccaria) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GFSKPLHYPPVRRDETVVDDYFGVKVADPYRWLEDPNSEETKEFVDNQEK
LANSVLEECELIDKFKQKIIDFVNFPRCGVPFRRANKYFHFYNSGLQAQN
VFQMQDDLDGKPEVLYDPNLREGGRSGLSLYSVSEDAKYFAFGIHSGLTE
WVTIKILKTEDRSYLPDTLEWVKFSPAIWTHDNKGFFYCPYPPAVNQEAR
YHFLGTDQSEDILLWRDLENPAHHLKCQITDDGKYFLLYILDGCDDANKV
YCLDLTKLPNGLESFRDSAPFMKLIDSFDASYTAIANDGSVFTFQTNKDA
PRKKLVRVDLNNPSVWTDLVPESKKDLLESAHAVNENQLILRYLSDVKHV
LEIRDLESGALQHRLPIDIGSVDGITARRRDSVVFFKFTSILTPGIVYQC
DLKNDPTQLKIFRESVVPDFDRSEFEVKQVFVPSKDGTKIPIFIAARKGI
SLDGSHPCEMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEY
GEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRVAIEGGANGGLLV
AACINQRPDLFGCAEANCGVMDMLRFHKFTLGYLWTGDYGCSDKEEEFKW
LIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATM
QHVLCTSLEDSPQKNPIIARIQRKAAHYGRATMTQIAEVADRYGFMAKAL
EAPWID
Ligand information
>5o3u Chain N (length=17) Species: 39387 (Gypsophila vaccaria) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
FSASYSSKPIQNASAPV
Receptor-Ligand Complex Structure
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PDB5o3u Characterization of the Fast and Promiscuous Macrocyclase from Plant PCY1 Enables the Use of Simple Substrates.
Resolution1.86 Å
Binding residue
(original residue number in PDB)		R81 F86 F95 A102 N104 L132 S133 Y135 F178 P180 C259 Y481 F484 I486 F492 S493 A494 S495 G561 A562 N563 N585 W603 R655 H695 T700
Binding residue
(residue number reindexed from 1)		R77 F82 F91 A98 N100 L128 S129 Y131 F174 P176 C244 Y463 F466 I468 F474 S475 A476 S477 G543 A544 N545 N567 W585 R637 H677 T682
Enzymatic activity
Enzyme Commision number 3.4.21.-
3.4.21.26: prolyl oligopeptidase.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0046872 metal ion binding
GO:0070012 oligopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5o3u, PDBe:5o3u, PDBj:5o3u
PDBsum5o3u
PubMed29377663
UniProtR4P353

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