Structure of PDB 5njf Chain C Binding Site BS01

Receptor Information

>5njf Chain C (length=480) Species: 83333 (Escherichia coli K-12)

SLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLE
DRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVR
DSGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKR
VQEVTASLSGVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGA
SGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSAVAAPAGTMPVV
LGAGWPGVLLAEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGT
MVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGR
RESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSD
KFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGV
GVCGKEGQSLPVGVGQPTLKVDNLTVGGTA

Ligand information

>5njf Chain F (length=5) Species: 511145 (Escherichia coli str. K-12 substr. MG1655)

AAAAA

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5njf The Origins of Specificity in the Microcin-Processing Protease TldD/E.
• Resolution: 1.42 Å
• Binding residue (original residue number in PDB): R184 W256 E263 G394 Q395 V396 V451 V453 G455
• Binding residue (residue number reindexed from 1): R183 W255 E262 G393 Q394 V395 V450 V452 G454

Enzymatic activity

• Enzyme Commision number: 3.4.-.-

Gene Ontology

Molecular Function

• GO:0005506 iron ion binding
• GO:0005515 protein binding
• GO:0008237 metallopeptidase activity
• GO:0008270 zinc ion binding

Biological Process

• GO:0006508 proteolysis
• GO:0016485 protein processing

Cellular Component

• GO:0005829 cytosol
• GO:1905368 peptidase complex

External links

• PDB: RCSB:5njf, PDBe:5njf, PDBj:5njf
• PDBsum: 5njf
• PubMed: 28943336
• UniProt: P0AGG8|TLDD_ECOLI Metalloprotease TldD (Gene Name=tldD)