Structure of PDB 5nj5 Chain C Binding Site BS01

Receptor Information
>5nj5 Chain C (length=479) Species: 511145 (Escherichia coli str. K-12 substr. MG1655) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLED
RIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRD
SGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRV
QEVTASLSGVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGAS
GGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVL
GAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTM
VDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGRR
ESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSDK
FVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVG
VCGKEGQSLPVGVGQPTLKVDNLTVGGTA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5nj5 Chain C Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5nj5 The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		H262 H267 C454
Binding residue
(residue number reindexed from 1)		H260 H265 C452
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.-.-
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0016485 protein processing
Cellular Component
GO:0005829 cytosol
GO:1905368 peptidase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5nj5, PDBe:5nj5, PDBj:5nj5
PDBsum5nj5
PubMed28943336
UniProtP0AGG8|TLDD_ECOLI Metalloprotease TldD (Gene Name=tldD)

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