Structure of PDB 5mrc Chain C Binding Site BS01

Receptor Information
>5mrc Chain C (length=249) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STRPFLVAPSIANSITTEAPAINHSPELANARKWLPKRCGLITRKKGMMP
YFDKSTGERSAATILEVNNVEVIMHRTSEVNGYFACQVGYGSRHLSKVSR
QMLGHFASKVVNPKEHVAEFRVKDEKGLIPPGTLLKPSFFKEGQYVDVRS
VSKGKGFTGVMKRYGFKGLRASHGTSIMHRHGGSYGQNQDPGRVLPGRKM
PGHMGNEHVTIQNVKVLKVDDENNVIWVKGSVAGPKNSFVKIQDAIKKT
Ligand information
>5mrc Chain A (length=2709) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guagaauaauagauuugaaauauuuauuauauagauuuaaagagauaauc
auggaguauaauaauuaaauuuaauuuaauauaacuauuaauagaagguu
acuaauaaauuaauaauuaauuuuaaaaccuaaagguaaaccuuuauauu
aauaauguuaugaauaauuauuaauaauaauaaacuaagugaacugaaac
aucuaaguaacuuaaggauaagaaaucaacagagauauuaugaguauugg
ugagagaaaauaauaaaggucuaauaaguauuaugugaaaaaaauguaag
aaaauaggauaacaaauucuaagacuaaauacuauuaauaaguauaguaa
guaccguaagggaaaguaugaaaaugauuauuuuauaagcaaucaugaau
auauuauauuauauuaaugauguaccuuuuguauaaugggucagcaagua
auuaauauuaguaaaacaauaaguuauaaauaaauagaauaauauauaua
uauaaaaaaauauauauuuaauuaauauuaauugacccgaaagcaaacga
ucuaacuaugauaagauggauaaacgaucgaacagguugauguugcaaua
ucaucugauuaauugugguuaguagugaaagacaaaucugguuugcagau
agcugguuuucuaugaaauauauguaaguauagccuuuauaaauaauaau
uauuauauaauauauuauauaaagaaugguacagcaauuaauauauauua
gggaacuaguuuuuuaauaauauuaaaucucgaaauauuuaauuauauau
aauaaagagucagauuaugugcgauaagguaaauaaucuaaagggaaaca
gcccagauuaagauauaaaguuccuaauaaauaauaagugaaauaaauau
uaaaauaaauauuuaaaaucaaauauauauauauuuguuaauagauaaua
uacggaucuuaauaauaagaauuauuuaauuccuuggaauauuauauuuu
aaaauauaaauacugaauaucuaaauauuauuauuauaauaauaauaaua
ugguaauagaacauuuaaugauaauauauauuaguuauuaauuaauauau
guauuaauuaaauagagaaugcugacaugaguaacgaaaaaaagguauaa
accuuuucaccuaaaacauaagguuuaacuauaaaaguacggccccuaau
uaaauuaaauauaaauauauuuaagaugggauaaucuauauuaauauuua
ucuuaaaauauauaauuauauuauauauuauauauuuauauaauauaaac
uaauaaagaucaggaaaauuaauguauaccguaauguagaccgacucagg
uauguaaguagagaauaugaaggugaauuagauaauuaaagggaaggaac
ucggcaaagauagcucauaaguuagucaauaaagaguaauaagaacaaag
uuguacaacuguuuacuaaaaacaccgcacuuugcagaaacgauaaguuu
aaguauaaggugugaacucugcuccaugcuuaauauauaaauaaaauuau
uuaacgauaauuuaauuaaauuuagguaaauagcagccuuauuaugaggg
uuauaauguagcgaaauuccuuggccuauaauugaggucccgcaugaaug
acguaaugauacaacaacugucuccccuuuaagcuaagugaaauugaaau
cguagugaagaugcuauguaccuucagcaagacggaaagacccuaugcag
cuuuacuguaauuagauagaucgaauuauuguuuauuauauauaaugaua
auucuaaucuuauacuuaauucuuaaguaauauauaauauauauauauau
uauauauuauaagagacaaucucuaauugguaguuuugauggucauuauc
agcaaaaguaucugaauaaguccauaaauaaauauauaaaauuauugaaa
aaaauaauauauauuauauauauuaauuauaaauugaaauauguuuaauu
gaauauauuuuaguaauagauaaaaauauguacaguaaaauuguaaggaa
aacaauaauaacuuucucggaaagaauuaaauuaauauaaugguauaacu
gugcgauaauuguaacacaaacgagugaaacaaguacguaaguauggcau
aaugaacaaauaacacugauuguaaagguuauugauaacgaauaaaaguu
acgcuagggaaggguaauauagcgaaagaguagauauuguaagcuauguu
ugccaccuucgacucaacauuuccucuugguuguaaaagcuaagaagggu
uugacuguucgucaauuaaaauguuacgugaguuggguuaaauacgaugu
gaaucaguaugguuccuaucugcugaaggaaauauuaucaaauuaaaucu
cauuauuaguacgcaaggaccauaaugaaucaacccaugguguaucuauu
gauaauaauauaauauauuuauuaauauauuaucuauauuaguuuauauu
uuaauuauuaucauaguagauaagcuaaguugauaauaaauaaauauuga
auacauauuaaauaugaaguuguuuuaauaagauaauuaaucugauaauu
uuauacuaaaauuaauaauuauagguuuuauauauuauuuauaauuauaa
uauuaauaaaauacuaauuuaucaguuaucuauauaauaucuaaucuauu
auucuauau
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...>>....>>>>>>...<<<.........<<<<<<.......>>>>>>.
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....>>>>>>>>>..>>>>>>..>>>..>>>>>>..<<<.<..<<<<<..
..........>>>>>...>>>>.>>>>>>..>>>>>.....<<<<<<<<<
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>>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5mrc The structure of the yeast mitochondrial ribosome.
Resolution3.25 Å
Binding residue
(original residue number in PDB)
S21 R23 H44 R52 K53 W54 K65 M68 P70 R79 A81 R96 Y103 R113 H114 K117 S119 R120 Q121 M122 G124 H125 S128 K129 E139 R141 R169 S172 K173 G174 K175 G176 F177 G179 M181 K182 R183 F186 K187 G188 L189 R190 A191 S192 H193 G194 T195 S196 I197 M198 H199 R200 H201 G202 G203 S204 Y205 G206 Q207 N208 Q209 D210 P211 G212 R213 V214 P216 G217 R218 M220 P221 H223 E227 H228 T230 Q232 N233 S251 V252 A253 G254 K267
Binding residue
(residue number reindexed from 1)
S1 R3 H24 R32 K33 W34 K45 M48 P50 R59 A61 R76 Y83 R93 H94 K97 S99 R100 Q101 M102 G104 H105 S108 K109 E119 R121 R149 S152 K153 G154 K155 G156 F157 G159 M161 K162 R163 F166 K167 G168 L169 R170 A171 S172 H173 G174 T175 S176 I177 M178 H179 R180 H181 G182 G183 S184 Y185 G186 Q187 N188 Q189 D190 P191 G192 R193 V194 P196 G197 R198 M200 P201 H203 E207 H208 T210 Q212 N213 S231 V232 A233 G234 K247
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5mrc, PDBe:5mrc, PDBj:5mrc
PDBsum5mrc
PubMed28154081
UniProtP31334|RM09_YEAST Large ribosomal subunit protein uL3m (Gene Name=MRPL9)

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