Structure of PDB 5m3j Chain C Binding Site BS01

Receptor Information
>5m3j Chain C (length=730) Species: 1601067 (Influenza B virus (B/Memphis/13/2003)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTLAKIELLKQLLRDNEAKTVLKQTTVDQYNIIRKFNTSRIEKNPSLRMK
WAMCSNFPLALTKGDMANRIPLEYKGIQLKTNAEDIGTKGQMCSIAAVTW
WNTYGPIGDTEGFERVYESFFLRKMRLDNATWGRITFGPVERVRKRVLLN
PLTKEMPPDEASNVIMEILFPKEAGIPRESTWIHRELIKEKREKLKGTMI
TPIVLAYMLERELVARRRFLPVAGATSAEFIEMLHCLQGENWRQIYHPGG
NKLTESRSQSMIVACRKIIRRSIVASNPLELAVEIANKTVIDTEPLKSCL
AAIDGGDVACDIIRAALGLKIRQRQRFGRLELKRISGRGFKNDEEILIGN
GTIQKIGIWDGEEEFHVRCGECRGILKKSKMKLEKLLINSAKKEDMRDLI
ILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFDQ
WGYEESPKASELHGINESMNASDYTLKGVVVTRNVKVSITKNLSLIKRTG
EVIMGANDVSELESQAQLMITYDTPKMWEMGTTKELVQNTYQWVLKNLVT
LKAQFLLGKEDMFQWDAFEAFESIIPQKMAGQYSGFARAVLKQMRDQEVM
KTDQFIKLLPFCFSPPKLRSNGEPYQFLKLVLKGGGENFIEVRKGSPLFS
YNPQTEVLTICGRMMSLKGKIEDEERNRSMGNAVLAGFLVSGKYDPDLGD
FKTIEELEKLKPGEKANILLYQGKPVKVVK
Ligand information
Receptor-Ligand Complex Structure
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PDB5m3j Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		T38 S39 R40 E42 R48 W51
Binding residue
(residue number reindexed from 1)		T38 S39 R40 E42 R48 W51
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694 viral RNA genome replication
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5m3j, PDBe:5m3j, PDBj:5m3j
PDBsum5m3j
PubMed28002402
UniProtQ5V8X3

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