Structure of PDB 5lrg Chain C Binding Site BS01

Receptor Information
>5lrg Chain C (length=304) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKP
GPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDF
YVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTG
ASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILY
PYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGS
DDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYV
LGHL
Ligand information
Receptor-Ligand Complex Structure
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PDB5lrg Isolation, Co-Crystallization and Structure-Based Characterization of Anabaenopeptins as Highly Potent Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa).
Resolution2.02 Å
Binding residue
(original residue number in PDB)		H69 R71 M125 R127 N144 R145 E163 Y198 S207 Y248 D255 E270 F279
Binding residue
(residue number reindexed from 1)		H64 R66 M120 R122 N139 R140 E158 Y194 S203 Y244 D251 E266 F275
Enzymatic activity
Catalytic site (original residue number in PDB) H69 E72 R127 H196 E270
Catalytic site (residue number reindexed from 1) H64 E67 R122 H192 E266
Enzyme Commision number 3.4.17.2: carboxypeptidase B.
Gene Ontology
Molecular Function
GO:0004181 metallocarboxypeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5lrg, PDBe:5lrg, PDBj:5lrg
PDBsum5lrg
PubMed27604544
UniProtP09955|CBPB1_PIG Carboxypeptidase B (Gene Name=CPB1)

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