Structure of PDB 5lgy Chain C Binding Site BS01

Receptor Information
>5lgy Chain C (length=197) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQ
LWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHL
IRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMG
GMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRK
Ligand information
Receptor-Ligand Complex Structure
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PDB5lgy Structural Basis for p53 Lys120-Acetylation-Dependent DNA-Binding Mode.
Resolution2.92 Å
Binding residue
(original residue number in PDB)		S241 R248 R273 C275 A276 R280
Binding residue
(residue number reindexed from 1)		S147 R154 R179 C181 A182 R186
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5lgy, PDBe:5lgy, PDBj:5lgy
PDBsum5lgy
PubMed27338200
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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