Structure of PDB 5lax Chain C Binding Site BS01

Receptor Information
>5lax Chain C (length=179) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRF
ASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELRE
PNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL
PFLPSTEDVYDCRVEHWGLDEPLLKHWEF
Ligand information
Receptor-Ligand Complex Structure
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PDB5lax Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted alpha-Enolase T Cell Epitope in Rheumatoid Arthritis.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		Q9 W43 G49 R50 F51 A52 S53 F54 N62 D66 N69 R76
Binding residue
(residue number reindexed from 1)		Q8 W42 G48 R49 F50 A51 S52 F53 N61 D65 N68 R75
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5lax, PDBe:5lax, PDBj:5lax
PDBsum5lax
PubMed27895642
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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