Structure of PDB 5jre Chain C Binding Site BS01

Receptor Information
>5jre Chain C (length=186) Species: 228908 (Nanoarchaeum equitans Kin4-M) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMLPNLDNLKEEYQKLEEKKQEIVDRSIRMSKLSKSLIYSMIREDYKSAD
KYKEELTNLAKTQIEELKKYPMFYSNGFIGLQEYVEALALYYYIKENRIP
SKEELGVDTWVYLFGIGDIAGEILRKSSEELIKGNIEYAKKAKQDLESLY
LDLLYIELKNFDLRRKLDYVSNIINKLIEFIIWKSK
Ligand information
Ligand IDADZ
InChIInChI=1S/C6H7N5/c1-11-3-10-4-5(7)8-2-9-6(4)11/h2-3H,1H3,(H2,7,8,9)
InChIKeyWRXCXOUDSPTXNX-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cn1cnc2c(N)ncnc12
OpenEye OEToolkits 1.5.0Cn1cnc2c1ncnc2N
ACDLabs 10.04n1c(c2ncn(c2nc1)C)N
FormulaC6 H7 N5
Name9-METHYL-9H-PURIN-6-AMINE
ChEMBLCHEMBL65976
DrugBank
ZINCZINC000000330548
PDB chain5jre Chain C Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5jre Structural basis for single-stranded RNA recognition and cleavage by C3PO
Resolution2.1 Å
Binding residue
(original residue number in PDB)		S74 W109 F113
Binding residue
(residue number reindexed from 1)		S75 W110 F114
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:5jre, PDBe:5jre, PDBj:5jre
PDBsum5jre
PubMed27596600
UniProtQ74ML9

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