Structure of PDB 5jnb Chain C Binding Site BS01

Receptor Information
>5jnb Chain C (length=289) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAMDVLSEKIWDYHNKVSQTDEMLQRKLHLRDMLYTAISPVFPLSGLYVV
GSSLNGFGNNSSDMDLCLMITNKDLDQKNDAVVVLNLILSTLQYEKFVES
QKLILAKVPILRINFAAPFDDITVALNANNSVAIRNTHLLCYYSSYDWRV
RPLVSVVKEWAKRKGIFTSYSLVLMVIHFLQCGPTKVLPNLQQSYPNRFS
NKVDVRTLNVTMALESLSEKTTLGELLIGFLDYYANEFNYDRDAISIRQG
RRVERAWRCVCIEEPFKKAFREAHGELQHNHDLDKLMEC
Ligand information
>5jnb Chain G (length=28) Species: 6239 (Caenorhabditis elegans) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
IDFRFDDYVEGAKRFDNLANLIRSSTPT
Receptor-Ligand Complex Structure
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PDB5jnb Structural basis for the antagonistic roles of RNP-8 and GLD-3 in GLD-2 poly(A)-polymerase activity.
Resolution2.486 Å
Binding residue
(original residue number in PDB)
R574 L587 G589 L590 Y591 V592 L597 G599 M612 I613 T614 N615 C684 Y685 S688 W691 R694 R756 V760
Binding residue
(residue number reindexed from 1)
R31 L44 G46 L47 Y48 V49 L54 G56 M69 I70 T71 N72 C141 Y142 S145 W148 R151 R206 V210
Enzymatic activity
Enzyme Commision number 2.7.7.19: polynucleotide adenylyltransferase.
External links
PDB RCSB:5jnb, PDBe:5jnb, PDBj:5jnb
PDBsum5jnb
PubMed27288313
UniProtO17087|GLD2_CAEEL Poly(A) RNA polymerase gld-2 (Gene Name=gld-2)

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