Structure of PDB 5j32 Chain C Binding Site BS01
Receptor Information
>5j32 Chain C (length=356) Species:
3702
(Arabidopsis thaliana) [
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KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDL
VGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALK
VFANLRPATVLPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKT
NENGEEVGFNTEVYAAHEIDRIARVAFETARKRRGKLCSVDKANVLEASI
LWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDIL
SDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATIL
SAAMLLKYGLGEEKAAKRIEDAVLVALNNGFRTGDIYSAGTKLVGCKEMG
EEVLKS
Ligand information
Ligand ID
MG
InChI
InChI=1S/Mg/q+2
InChIKey
JLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341
[Mg++]
Formula
Mg
Name
MAGNESIUM ION
ChEMBL
DrugBank
DB01378
ZINC
PDB chain
5j32 Chain C Residue 501 [
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Receptor-Ligand Complex Structure
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PDB
5j32
Structure and Mechanism of Isopropylmalate Dehydrogenase from Arabidopsis thaliana: INSIGHTS ON LEUCINE AND ALIPHATIC GLUCOSINOLATE BIOSYNTHESIS.
Resolution
1.933 Å
Binding residue
(original residue number in PDB)
D288 D292
Binding residue
(residue number reindexed from 1)
D248 D252
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
L48 Y181 K232 D264 D288 D292
Catalytic site (residue number reindexed from 1)
L8 Y141 K192 D224 D248 D252
Enzyme Commision number
1.1.1.85
: 3-isopropylmalate dehydrogenase.
Gene Ontology
Molecular Function
GO:0000287
magnesium ion binding
GO:0003862
3-isopropylmalate dehydrogenase activity
GO:0016491
oxidoreductase activity
GO:0016616
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042803
protein homodimerization activity
GO:0046872
metal ion binding
GO:0051287
NAD binding
GO:0070403
NAD+ binding
Biological Process
GO:0009098
L-leucine biosynthetic process
GO:0009553
embryo sac development
GO:0009555
pollen development
Cellular Component
GO:0005829
cytosol
GO:0009507
chloroplast
GO:0009536
plastid
GO:0009570
chloroplast stroma
GO:0009941
chloroplast envelope
View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:5j32
,
PDBe:5j32
,
PDBj:5j32
PDBsum
5j32
PubMed
27137927
UniProt
P93832
|LEU32_ARATH 3-isopropylmalate dehydrogenase 2, chloroplastic (Gene Name=IMDH2)
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