Structure of PDB 5h4p Chain C Binding Site BS01 |
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| >5h4p Chain 1 (length=3091)
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uugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaauaa
gcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagc
ggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaau
uuggagagggcaacuuuggggccguuccuugucuauguuccuuggaacag
gacgucauagagggugagaaucccguguggcgaggagugcgguucuuugu
aaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcauuugaucagacaggccagcaucag
uuuugguggcaggauaaauccauaggaauguagcuugccucgguaaguau
uauagccugugggaauacugccagcugggacugaggacugcgacguaagu
caaggaugcuggcauaaugguuauaugccgcccgucuugaaacacggacc
aaggagucuaacgucuaugcgaguguuuggguguaaaacccauacgcgua
augaaagugaacguagguuggggccucgcaagaggugcacaaucgaccga
uccugaugucuucggauggauuugaguaagagcauagcuguugggacccg
aaagauggugaacuaugccugaauagggugaagccagaggaaacucuggu
ggaggcucguagcgguucugacgugcaaaucgaucgucgaauuuggguau
aggggcgaaagacuaaucgaaccaucuaguagcugguuccugccgaaguu
ucccucaggauagcagaagcucguaucaguuuuaugagguaaaguuaaau
auguaagaaguccuuguuacuuaauugaacguggacauuugaaugaagag
cuuuuagugggccauuuuugguaagcagaacuggcgaugcgggaugaacc
gaacguagaguuaaggugccggaauacacgcucaucagacaccacaaaag
guguuaguucaucuagacagccggacgguggccauggaagucggaauccg
cuaaggaguguguaacaacucaccggccgaaugaacuagcccugaaaaug
gauggcgcucaagcguguuaccuauacucuaccgucaggguugauaugau
gcccugacgaguaggcaggcguggaggucagugacgaagccuagaccgua
aggucgggucgaacggccucuagugcagaucuuggugguaguagcaaaua
uucaaaugagaacuuugaagacugaaguggggaaagguuccacgucaaca
gcaguuggacguggguuagucgauccuaagagauggggaagcuccguuuc
aaaggccugauuuuaugcaggccaccaucgaaagggaauccgguuaagau
uccggaaccuggauauggauucuucacgguaacguaacugaauguggaga
cgucggcgcgagcccugggaggaguuaucuuuucuucuuaacagcuuauc
accccggaauugguuuauccggagauggggucuuauggcuggaagaggcc
agcaccuuugcuggcuccggugcgcuugugacggcccgugaaaauccaca
ggaaggaauaguuuucaugccaggucguacugauaaccgcagcaggucuc
caaggugaacagccucuaguugauagaauaauguagauaagggaagucgg
caaaauagauccguaacuucgggauaaggauuggcucuaagggucgggua
cgaucaacuuagaacugguacggacaaggggaaucugacugucuaauuaa
aacauagcauugcgauggucagaaagugauguugacgcaaugugauuucu
gcccagugcucugaaugucaaagugaagaaauucaaccaagcgcggguaa
acggcgggaguaacuaugacucucuuaagguagccaaaugccucgucauc
uaauuagugacgcgcaugaauggauuaacgagauucccacugucccuauc
uacuaucuagcgaaaccacagccaagggaacgggcuuggcagaaucagcg
gggaaagaagacccuguugagcuugacucuaguuugacauugugaagaga
ucuuuacuuauucaaugaagcggagcuggaauucauuuuccacguucuag
cauucaaggucccauucggggcugauccggguugaagacauugucaggug
gggaguuuggcuggggcggcacaucuguuaaacgauaacgcagauguccu
aaggggggcucauggagaacagaaaucuccaguagaacaaaaggguaaaa
gcccccuugauuuugauuuucagugugaauacaaaccaugaaaguguggc
cuaucgauccuuuagucccucggaauuugaggcuagaggugccagaaaag
uuaccacagggauaacuggcuuguggcagucaagcguucauagcgacauu
gcuuuuugauucuucgaugucggcucuuccuaucauaccgaagcagaauu
cgguaagcguuggauuguucacccacuaauagggaacgugagcuggguuu
agaccgucgugagacagguuaguuuuacccuacugaugaauguuaccgca
auaguaauugaacuuaguacgagaggaacaguucauucggauaauugguu
uuugcggcugucugaucaggcauugccgcgaagcuaccauccgcuggauu
auggcugaacgccucuaagucagaauccaugcuagaacgcggugauuucu
uugcuccacacaauauagauggauacgaauaaggcguccuuguggcgucg
cugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugggu
gcuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuugua
uacgacuuagauguacaacgggguauuguaagcaguagaguagccuuguu
guuacgaucugcugagauuaagccuuuguugucugauuugu |
........................<<<<<<.....<......>......>
>>>>.>.........<<....>>..<<<<<......<<.....>>.....
>>>>>..<<<...<.......<<.<<<<<<...>>>>>>.>>.......>
.....<<<<<<<.<<<<<<<<<<<<<<<<<<<<<....<<<<......>>
>>.(.......<<<......)>>>..>.>>>>>>>>..>>>>>>>>....
>>>>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<
<..((((((>>>>>..>>>...............................
...<<....>>...............<<<......>>>............
......................<<<<<.<<<<<......<<<<<<<.<<<
<<<<<<<<<<<<.....<<<<<<<<<......<<<<<......>>>>>..
.....>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<....>>
>.....>>>>>>>.....>>>>>.>>>>>..<<<<........>>>><<<
<<<....<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>...
<<....>>.......<<<<<..<<<<<....>>>>>...>>>>>.<<<<<
<<<....<....>....>>>.>>>.>>....>>>>>>.>>>>>>..<<.<
..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....>>>>>>>
.....>>>...<<<..<<.<<........>>>>.>>>....>>>>>>>>>
...<<.......>>......>>>>>>...>..>.>>..<<<<<<....<.
<<<....>>>.><<<<<<<<<<...<<<.<<<<<<<.....<<.>>....
.>>>>>...<<<<.<<<<.<......>>>>>.>>>>.....>>>>>.>>>
>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>
>...<<<<<<<..<<<<(((.....<<<<<<......<..........<<
<.<<<<<<<<<........<<<<<.<<....<<.........>>....>>
.........<<......>>...>>>>>....>>>>>>>>>>>>.......
...))).>....>>>>>>.>>>>..>>>>>>><<<<<<<<<.........
>>>>>>>>>....>>>>>><.<<<<<<<..<<......<<<<.<<<<...
.>>>>>>>>...>>.>>>>>>>..>.....>>>>>><<.....<<.....
<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<...<<
.....>>.>>>>>>....((<<<<<<...<<....<<<....>>>.....
...<<<<<<........>>>>>>....>>....>>...<<<<<.......
.>>>>>))<<<<.<<<<<<<.....<<<....>>>.......<<<<<<..
.<<<<.<<<<<<<.<<<<<<<<<<..[[[..>>>>>><...<<<<<....
<<<<<<....<<<.....>>>....>>>>>>.....>>>>>....><<<<
<<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>
..........>>>..>>>>>>>>>>>>..>>.....<<......>>>>>>
>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<.<<........
.<.....<<<<<....<....>.....>>>>><<.<<<<<<<<<<.<...
>>>>>..>>>>>>.>>............<<<<<<<<<..<<<........
.>>>..<<<<<<<....<<<<.....>>>>......>>>>>>>...<<..
<<<..<<<<<<.<...<<....<<<<<....>>>>.>...>>.>>>>>..
>>>>><<<<<.........>>>>>........<...........<<<<<.
......>>>>>.....>.....>>....>>.>>>>>>>..>..>>.>>>>
>>>..>>>>>>....>>....<<<<<........>>>>>....<<<<<..
<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<..<<<<<<<..
>>>>>>>...<<<<<.....<<<<..<<<<<......>>>>>........
.......<<<<<<....>>>>>>..>>>>..>>>>>.....>>>>>>>>.
.>>>>>...<<<.....>>>..<<<<<<...........>>>>>>..<<.
..<<<<<<<...<<<<<<.......>>>>>>.....<<...(((>>....
>>>>>>>...<<<.<<<<<.......>>>>.>>>>.<<<....>>>.>>)
))......<<<<<<<..<<<<.))))))>>>>>>>>>>>.........>>
>>..>>>>>>.......<<.<...<<<<<<...<<.......>>...>>>
>>>....>.>.>.......<.<<<.<<<<<<..<.<<<<<<<......>>
>>>>>...>.<<<.........>>>.....>>>>>..>...>>>..>...
.<<<<<<<....>>>.>>>>....>>..>>>.>>>>>....<<<<<<<<.
.<<<<...<<<<<<...............>>>>>>..<<<<<...<<<<.
...<<<<<<<<<.]]]..>>>>..>>>>>...>>>>..>>>>>.<<<<..
.<<<<<...........>>>>>...>>>>.>>>>....>>>>>>>>....
...<<<<<<.<<<.<<....<<..........<<<<<<.....>>>>>>.
.....>>.......<<<<<<...<<<<<.<..<<<......>>>..>.>>
>>>.>>>>>>.............>>.>>>.>>>>>>..<<<<<.<.....
........>.....<<<<<<<<<.<<<....<<<<....<<<<<......
>>>>>...>>>>...>>>....>>>>.>>>>>..>>>>>.. |
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| PDB | 5h4p Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1 |
| Resolution | 3.07 Å |
Binding residue
(original residue number in PDB) | R31 H36 T40 K44 N45 R47 Q48 Y50 V52 S53 E54 A56 H58 Q59 S61 T67 G68 A70 V71 A72 R73 I74 P75 G80 G81 T82 Q87 N92 M93 R95 G96 R98 M99 F100 A101 P102 K104 R107 K108 K112 N114 H115 N116 K118 R119 R138 R141 K161 T162 K163 K183 K186 L187 R188 A189 G190 K191 K193 Y194 R195 R197 W199 R202 R203 Y209 K217 R220 N221 P223 T227 N234 P240 G241 H243 K271 V272 I290 N291 R300 A302 G303 A305 Q307 K308 R309 V312 L313 K315 N320 Q322 R326 N328 Y330 A331 K332 F334 A335 G340 S341 K342 K343 A344 T347 T349 |
Binding residue
(residue number reindexed from 1) | R30 H35 T39 K43 N44 R46 Q47 Y49 V51 S52 E53 A55 H57 Q58 S60 T66 G67 A69 V70 A71 R72 I73 P74 G79 G80 T81 Q86 N91 M92 R94 G95 R97 M98 F99 A100 P101 K103 R106 K107 K111 N113 H114 N115 K117 R118 R137 R140 K160 T161 K162 K182 K185 L186 R187 A188 G189 K190 K192 Y193 R194 R196 W198 R201 R202 Y208 K216 R219 N220 P222 T226 N233 P239 G240 H242 K270 V271 I289 N290 R299 A301 G302 A304 Q306 K307 R308 V311 L312 K314 N319 Q321 R325 N327 Y329 A330 K331 F333 A334 G339 S340 K341 K342 A343 T346 T348 |
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