Structure of PDB 5fvc Chain C Binding Site BS01

Receptor Information
>5fvc Chain C (length=346) Species: 162145 (human metapneumovirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQGIHLSDLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGEIL
YAKHADYKYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYQMLD
IHGVEKSWVEEIDKEARKTMATLLKESSGNIPQNQRPSAPDTPIILLCVG
ALIFTKLASTIEVGLETTVRRANRVLSDALKRYPRMDIPKIARSFYDLFE
QKVYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTMLRWGVIA
RSSNNIMLGHVSVQAELKQVTEVYDLVREMGPESGLLHLRQSPKAGLLSL
ANCPNFASVVLGNASGLGIIGMYRGRVPNTELFSAAESYAKSLKES
Ligand information
>5fvc Chain K (length=70) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccccccccccccccccccccccccccccccccccccccccccccccccc
cccccccccccccccccccc
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Receptor-Ligand Complex Structure
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PDB5fvc Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein.
Resolution4.17 Å
Binding residue
(original residue number in PDB)		K171 S174 R185 R186 R189 V190 L243 N246 Q250 G255 T257 M258 W261 S314 M337 Y338 R339 G340 R341
Binding residue
(residue number reindexed from 1)		K156 S159 R170 R171 R174 V175 L228 N231 Q235 G240 T242 M243 W246 S299 M322 Y323 R324 G325 R326
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5fvc, PDBe:5fvc, PDBj:5fvc
PDBsum5fvc
PubMed26880565
UniProtQ91F57

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