Structure of PDB 5exh Chain C Binding Site BS01

Receptor Information
>5exh Chain C (length=45) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKRKRCGTCDPCRRLENCGSCTSCTNRRTHQICKLRKCEVLKKKA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5exh Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration.
Resolution1.3 Å
Binding residue
(original residue number in PDB)		K53 R54 H81 R87 K88 L92
Binding residue
(residue number reindexed from 1)		K2 R3 H30 R36 K37 L41
Binding affinityPDBbind-CN: Kd=0.56uM
Enzymatic activity
Enzyme Commision number 1.14.11.80: methylcytosine dioxygenase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5exh, PDBe:5exh, PDBj:5exh
PDBsum5exh
PubMed26774490
UniProtQ8BG87|TET3_MOUSE Methylcytosine dioxygenase TET3 (Gene Name=Tet3)

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