Structure of PDB 5eg6 Chain C Binding Site BS01

Receptor Information
>5eg6 Chain C (length=413) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLM
GSGWKKKKEQMERDGCSEQESQPCAFIGIGNSEMQQLNLEGKNYCTAKTL
YISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKQSLKNADLC
IASGTKVALFNRLTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGE
EFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQL
HKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIIST
DKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGDVAMLELTGQNFTPNLRV
WFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGV
IYSTSLTFTYTPE
Ligand information
Receptor-Ligand Complex Structure
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PDB5eg6 CSL-RITA complex bound to DNA
Resolution2.094 Å
Binding residue
(original residue number in PDB)
K84 Y86 S191 K192
Binding residue
(residue number reindexed from 1)
K32 Y34 S137 K138
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5eg6, PDBe:5eg6, PDBj:5eg6
PDBsum5eg6
PubMed
UniProtP31266|SUH_MOUSE Recombining binding protein suppressor of hairless (Gene Name=Rbpj)

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