Structure of PDB 5dmv Chain C Binding Site BS01
Receptor Information
>5dmv Chain C (length=230) Species:
10090
(Mus musculus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
CHLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKY
GLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNS
LMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAI
ILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYG
CCKELASRLRYARTMVDKLLSSRSASNRLK
Ligand information
>5dmv Chain D (length=11) Species:
10090
(Mus musculus) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
LVTSTIKTDVV
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5dmv
Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.
Resolution
2.499 Å
Binding residue
(original residue number in PDB)
K413 W414 D416 Q426 N430 S487 H489 L490 L491 K492 R516 H538 K540
Binding residue
(residue number reindexed from 1)
K42 W43 D45 Q55 N59 S116 H118 L119 L120 K121 R145 H167 K169
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:5dmv
,
PDBe:5dmv
,
PDBj:5dmv
PDBsum
5dmv
PubMed
26459104
UniProt
Q07832
|PLK1_MOUSE Serine/threonine-protein kinase PLK1 (Gene Name=Plk1)
[
Back to BioLiP
]
