Structure of PDB 5dkp Chain C Binding Site BS01

Receptor Information
>5dkp Chain C (length=191) Species: 122586 (Neisseria meningitidis MC58) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPTVIEQSGRGERAFDIYSRLLKERIVFLVGPVTDESANLVVAQLLFLES
ENPDKDIFFYINSPGGSVTAGMSIYDTMNFIKPDVSTLCLGQAASMGAFL
LSAGEKGKRFALPNSRIMIHQPLISGGLGGQASDIEIHARELLKIKEKLN
RLMAKHCDRDLADLERDTDRDNFMSAEEAKEYGLIDQILEN
Ligand information
Receptor-Ligand Complex Structure
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PDB5dkp Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial Activity.
Resolution2.381 Å
Binding residue
(original residue number in PDB)		F65 Y67 F117 L119 L196
Binding residue
(residue number reindexed from 1)		F58 Y60 F110 L112 L189
Enzymatic activity
Catalytic site (original residue number in PDB) G73 S102 M103 H127 D178
Catalytic site (residue number reindexed from 1) G66 S95 M96 H120 D171
Enzyme Commision number 3.4.21.92: endopeptidase Clp.
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0051117 ATPase binding
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
Cellular Component
GO:0005737 cytoplasm
GO:0009368 endopeptidase Clp complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5dkp, PDBe:5dkp, PDBj:5dkp
PDBsum5dkp
PubMed26818454
UniProtQ9JZ38|CLPP_NEIMB ATP-dependent Clp protease proteolytic subunit (Gene Name=clpP)

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