Structure of PDB 5af0 Chain C Binding Site BS01

Receptor Information
>5af0 Chain C (length=239) Species: 7091 (Bombyx mori) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
REMKNAEDNEKKDIQNIVKLKVFDQSIKTEDFYVIDVNSYCKANGDYLIG
EFTVTQFSLQDGVKNSYHETIIPSCVPVGYMFDVKLGAEEFGLEMPGAGP
NYIQILANIIDYLKQKDRTVQVLPPMFTLPEKVDAVQNFISQMCNCATED
DSLFRIYKLDTFFFTLINAISHHDEGFPKESLALTQLTKDPGIACERHES
LDKSNVCTTSRVKRWVFTILDRCCPLLGIPLQPGKHLPF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5af0 Chain C Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5af0 Metazoan Maelstrom is an RNA-Binding Protein that Has Evolved from an Ancient Nuclease Active in Protists.
Resolution2.401 Å
Binding residue
(original residue number in PDB)
E137 C290 H293 C302
Binding residue
(residue number reindexed from 1)
E51 C195 H198 C207
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0060964 regulation of miRNA-mediated gene silencing

View graph for
Biological Process
External links
PDB RCSB:5af0, PDBe:5af0, PDBj:5af0
PDBsum5af0
PubMed25778731
UniProtA0A0H5AXR2

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