Structure of PDB 4ypi Chain C Binding Site BS01

Receptor Information
>4ypi Chain C (length=348) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRVIPVYQVNNLEEICQLIIQAFEAGVDFQESADSFLLMLCLHHAYQGDY
KLFLESGAVKYLEGHGFRFEVKKRDGVKRLEELLPAVSSGKNIKRTLAAM
PEEETTEANAGQFLSFASLFLPKLVVGEKACLEKVQRQIQVHAEQGLIQY
PTAWQSVGHMMVIFRLMRTNFLIKFLLIHQGMHMVAGHDANDAVISNSVA
QARFSGLLIVKTVLDHILQKTERGVRLHPLARTAKVKNEVNSFKAALSSL
AKHGEYAPFARLLNLSGVNNLEHGLFPQLSAIALGVATAHGSTLAGVNVG
EQYQQLREAATEAEKQLQQYAESRELDHLGLDDQEKKILMNFHQKKNE
Ligand information
>4ypi Chain G (length=28) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MPGPELSGWISEQLMTGRIPVSDIFCDI
Receptor-Ligand Complex Structure
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PDB4ypi An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.
Resolution3.71 Å
Binding residue
(original residue number in PDB)		F241 K248 D252 L255 Q256 K257 L264 R269 K274 K281 L284 A288 G291 E292 H327 Q355
Binding residue
(residue number reindexed from 1)		F204 K211 D215 L218 Q219 K220 L227 R232 K237 K244 L247 A251 G254 E255 H290 Q318
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0019074 viral RNA genome packaging
Cellular Component
GO:0019013 viral nucleocapsid

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Biological Process
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Cellular Component
External links
PDB RCSB:4ypi, PDBe:4ypi, PDBj:4ypi
PDBsum4ypi
PubMed25865894
UniProtP18272|NCAP_EBOZM Nucleoprotein (Gene Name=NP)

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