Structure of PDB 4xgc Chain C Binding Site BS01

Receptor Information
>4xgc Chain C (length=567) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQPFYEEYRKAWNQINDHIADLQHRSYARTLEQLVDFVVGQAERDEVLPT
AALLTGINQPDHLSQFTALTQRLHAQRAAMVCVLQSRDCATLKAAVETLV
FGLVEDNAEVEQLRRSQCTMKQLKSWYTNNFDSEQKRRQLVVILPDFECF
NASVLQDLILILSAHCGSLPFVLVLGVATAMTAVHGTLPYHVSSKIRLRV
FQTQAAPTGLNEVLDKVLLSPKYAFHLSGKTFKFLTHIFLYYDFSIHGFI
QGFKYCLMEHFFGGNAFALCTDYSKALGRIKQLTHEDMETIRRLPSFRPY
VEQINDCKRIIAVLTDDDYLKKKLPQLLRDCLLHFLLFRCSLEFLTELVG
DLPRCPLGKLRRELYVNCLNRAIISTPEYKECLQMLSFLSKDEFVAKVNR
ALERTEQFLVEEIAPLELGEACTAVLRPKLEAIRLAVDEVGRALQKTLQL
IETQIVQDHLRALQDAPPIHELFVFSDIATVRRNIIGAPRAALHTALNNP
HFPDLSVVYKLHLECGRMINLFDWLQAFRSVVPQIQARFTRAVAELQFLG
YIKMSKRKTDHATRLTW
Ligand information
>4xgc Chain F (length=19) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EDYEIWKARMLAKAQAKLK
Receptor-Ligand Complex Structure
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PDB4xgc Crystal structure of the eukaryotic origin recognition complex.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		E354 R357 R358 R363 V366 C372 I376 L379
Binding residue
(residue number reindexed from 1)		E289 R292 R293 R298 V301 C307 I311 L314
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0007611 learning or memory
GO:0007612 learning
GO:0008355 olfactory learning
GO:0030536 larval feeding behavior
GO:1903688 positive regulation of border follicle cell migration
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xgc, PDBe:4xgc, PDBj:4xgc
PDBsum4xgc
PubMed25762138
UniProtQ7K2L1

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