Structure of PDB 4xdj Chain C Binding Site BS01
Receptor Information
>4xdj Chain C (length=224) Species:
9606
(Homo sapiens) [
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WKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVC
VSPQELETLIQHALDADNAGVSPIGNSHWDLGSAFFFAGTVITTIGYGNI
APSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIRVISTILFI
LAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAREWYKP
LVWFWILVGLAYFAAVLSMIGDWL
Ligand information
Ligand ID
K
InChI
InChI=1S/K/q+1
InChIKey
NPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[K+]
Formula
K
Name
POTASSIUM ION
ChEMBL
CHEMBL1233793
DrugBank
DB01345
ZINC
PDB chain
4xdj Chain C Residue 601 [
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Receptor-Ligand Complex Structure
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PDB
4xdj
K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.
Resolution
3.8 Å
Binding residue
(original residue number in PDB)
I173 G174 Y175 V282 G283 F284
Binding residue
(residue number reindexed from 1)
I95 G96 Y97 V187 G188 F189
Annotation score
5
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005267
potassium channel activity
Biological Process
GO:0071805
potassium ion transmembrane transport
Cellular Component
GO:0016020
membrane
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:4xdj
,
PDBe:4xdj
,
PDBj:4xdj
PDBsum
4xdj
PubMed
25766236
UniProt
P57789
|KCNKA_HUMAN Potassium channel subfamily K member 10 (Gene Name=KCNK10)
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