Structure of PDB 4xco Chain C Binding Site BS01

Receptor Information
>4xco Chain C (length=157) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEDMVDEKTEESIDAIMRGKFTLNELMTQLEAIENMGSMKKILSMIPGFG
GAMPKELSHLTEAKIKKYKVIISSMTKEERENPKIIKASRIRRIARGSGT
TENDVREVLRYYETTKNAIDKLRKGKMLRIGGPLGQIMRQLGKLALALLL
LLLALAL
Ligand information
>4xco Chain M (length=96) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcggugggggagcaucuccuguaggggagauguaacccccuuuaccugc
cgaaccccgccaggcccggaagggagcaacgguaggcaggacgucg
<<<<..<<<<<.<<<<<<<<<....>>>>>>>>>..>>>>>....<<<<<
<.....<<<...<.<<<....>>>..>..>>>..>>>>>>.>>>>.
Receptor-Ligand Complex Structure
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PDB4xco Signal-sequence induced conformational changes in the signal recognition particle.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		K429 K431
Binding residue
(residue number reindexed from 1)		K124 K126
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xco, PDBe:4xco, PDBj:4xco
PDBsum4xco
PubMed26051119
UniProtQ57565|SRP54_METJA Signal recognition particle 54 kDa protein (Gene Name=srp54)

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