Structure of PDB 4xaj Chain C Binding Site BS01

Receptor Information
>4xaj Chain C (length=568) Species: 9606,83333 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQV
AATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYN
GKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN
LQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIK
NKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLG
AVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINA
ASGRQTVDEALKDAQTNAAAEFTESVCESAARLLFMSIKWAKSVPAFSTL
SLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQRLT
LIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTLRSFRNAAAI
AALQDEAQLTLNSYIHTRYPTQPVRFGKLLLLLPALRSISPSTIEEVFFK
KTIGNVPITRLLSDMYKS
Ligand information
>4xaj Chain Q (length=18) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
YADTPALRQLSEYARPHV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4xaj Structural basis for corepressor assembly by the orphan nuclear receptor TLX.
Resolution3.551 Å
Binding residue
(original residue number in PDB)		E1183 C1186 E1187 A1190 F1363 K1365 T1366 L1376 Y1380
Binding residue
(residue number reindexed from 1)		E374 C377 E378 A381 F549 K551 T552 L562 Y566
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015144 carbohydrate transmembrane transporter activity
Biological Process
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport

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Molecular Function
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Biological Process
External links
PDB RCSB:4xaj, PDBe:4xaj, PDBj:4xaj
PDBsum4xaj
PubMed25691470
UniProtP0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
Q9Y466

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