Structure of PDB 4x4v Chain C Binding Site BS01

Receptor Information
>4x4v Chain C (length=431) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVEYVFVGSYARNT
WLKGSLEIDVFLLFPEEFSKEELRERGLEIGKAVLDSYEIRYAEHPYVHG
VVKGVEVDVVPCYKLKEPKNIKSAVDRTPFHHKWLEGRIKGKENEVRLLK
GFLKANGIYGAEYKVRGFSGYLCELLIVFYGSFLETVKNARRWTRRTVID
VAKGEVRKGEEFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEAPSLG
FFKPKIEPERLRKIVEERGTAVFAVKFRKPDIVDDNLYPQLERASRKIFE
FLERENFMPLRSAFKASEEFCYLLFECQIKEISRVFRRMGPQFEDERNVK
KFLSRNRAFRPFIENGRWWAFEMRKFTTPEEGVRSYASTHWHTLGKNVGE
SIREYFEIISGEKLFKEPVTAELCEMMGVKD
Ligand information
>4x4v Chain D (length=26) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcgcuggguucgaccccgcgccacc
<<<...<<<.....>>>...>>>...
Receptor-Ligand Complex Structure
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PDB4x4v On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		D61 F63 A95 E96 H97 Y99 V127 T130 A163 E164 Y165 R224 A228 N229 D291 N292 P295 Q296 R299 M345 G346 P347 N354 K357 F358 R361 H396 H398 T399 G401 K402
Binding residue
(residue number reindexed from 1)		D59 F61 A93 E94 H95 Y97 V125 T128 A161 E162 Y163 R222 A226 N227 D285 N286 P289 Q290 R293 M339 G340 P341 N348 K351 F352 R355 H390 H392 T393 G395 K396
Enzymatic activity
Enzyme Commision number 2.7.7.72: CCA tRNA nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0004810 CCA tRNA nucleotidyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0160016 CCACCA tRNA nucleotidyltransferase activity
Biological Process
GO:0001680 tRNA 3'-terminal CCA addition
GO:0008033 tRNA processing
GO:0031123 RNA 3'-end processing
GO:0042245 RNA repair
GO:0106354 tRNA surveillance

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Molecular Function
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Biological Process
External links
PDB RCSB:4x4v, PDBe:4x4v, PDBj:4x4v
PDBsum4x4v
PubMed25640237
UniProtO28126|CCA_ARCFU CCA-adding enzyme (Gene Name=cca)

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