Structure of PDB 4x4n Chain C Binding Site BS01

Receptor Information
>4x4n Chain C (length=436) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVEYVFVGSYARN
TWLKGSLEIDVFLLFPEEFSKEELRERGLEIGKAVLDSYEIRYAEHPYVH
GVVKGVEVDVVPCYKLKEPKNIKSAVDRTPFHHKWLEGRIKGKENEVRLL
KGFLKANGIYGAEYKVRGFSGYLCELLIVFYGSFLETVKNARRWTRRTVI
DVAKGEVRKGEEFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEAPSL
GFFKPKHPLEIEPERLRKIVEERGTAVFAVKFRKPDIVDDNLYPQLERAS
RKIFEFLERENFMPLRSAFKASEEFCYLLFECQIKEISRVFRRMGPQFED
ERNVKKFLSRNRAFRPFIENGRWWAFEMRKFTTPEEGVRSYASTHWHTLG
KNVGESIREYFEIISGEKLFKEPVTAELCEMMGVKD
Ligand information
>4x4n Chain D (length=31) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggccgcggcagguucgauccugccgcgaucg
<<.<<<<<<<<<......>>>>>>>>>.>>.
Receptor-Ligand Complex Structure
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PDB4x4n On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme.
Resolution2.953 Å
Binding residue
(original residue number in PDB)		A95 E96 A163 Y165 R224 A228 N229 D291 N292 P295 Q296 R299 R302 K303 M345 G346 P347 N354 K357 F358 H398 T399 G401 K402
Binding residue
(residue number reindexed from 1)		A94 E95 A162 Y164 R223 A227 N228 D290 N291 P294 Q295 R298 R301 K302 M344 G345 P346 N353 K356 F357 H397 T398 G400 K401
Enzymatic activity
Enzyme Commision number 2.7.7.72: CCA tRNA nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0004810 CCA tRNA nucleotidyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0160016 CCACCA tRNA nucleotidyltransferase activity
Biological Process
GO:0001680 tRNA 3'-terminal CCA addition
GO:0008033 tRNA processing
GO:0031123 RNA 3'-end processing
GO:0042245 RNA repair
GO:0106354 tRNA surveillance

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Molecular Function
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Biological Process
External links
PDB RCSB:4x4n, PDBe:4x4n, PDBj:4x4n
PDBsum4x4n
PubMed25640237
UniProtO28126|CCA_ARCFU CCA-adding enzyme (Gene Name=cca)

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