Structure of PDB 4x3n Chain C Binding Site BS01

Receptor Information
>4x3n Chain C (length=258) Species: 44689 (Dictyostelium discoideum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLSAEAMEFFCNVAKLPFSQQAVHFLNAYWAEVSKEAEFIYSVGWETIKY
ADMHCKGIQLVFKYDEGNDLDFDIALYFYEQLCKFCEDPKNKNYATTYPI
SQPQMLTALKRKQELREKVDVNFDGRVSFLEYLLYQYKDFANPADFCTRS
MNHDEHPEIKKARLALEEVNKRIRAYEEEKARLTEESKIPGVKGLGATNM
LAQIDSGPLKEQLNFALISAEAAVRTASKKYGGSSAGAIWWMNRDLEEKK
KRYGPQKK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4x3n Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4x3n Structure of the 34 kDa F-actin-bundling protein ABP34 from Dictyostelium discoideum.
Resolution1.89 Å
Binding residue
(original residue number in PDB)		D144 N146 D148 R150 E155
Binding residue
(residue number reindexed from 1)		D120 N122 D124 R126 E131
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005509 calcium ion binding
GO:0051015 actin filament binding
Biological Process
GO:0030046 parallel actin filament bundle assembly
GO:0051017 actin filament bundle assembly
GO:0051764 actin crosslink formation
Cellular Component
GO:0005737 cytoplasm
GO:0030175 filopodium
GO:0030863 cortical cytoskeleton
GO:0031143 pseudopodium
GO:0031941 filamentous actin
GO:0045335 phagocytic vesicle
GO:0061836 intranuclear rod

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4x3n, PDBe:4x3n, PDBj:4x3n
PDBsum4x3n
PubMed26327373
UniProtP24005|ACTB_DICDI Calcium-regulated actin-bundling protein (Gene Name=abpB)

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