Structure of PDB 4wj7 Chain C Binding Site BS01

Receptor Information
>4wj7 Chain C (length=129) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHD
AVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQE
ACCLVILAAESKVAAEELCCLLGQVFQVV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4wj7 Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations.
Resolution2.753 Å
Binding residue
(original residue number in PDB)		P82 S83 R85 H137 D138 I139 A140 A141 V142 S143 Y144 R146 C210 F217 V219 V220
Binding residue
(residue number reindexed from 1)		P22 S23 R25 H77 D78 I79 A80 A81 V82 S83 Y84 R86 C119 F126 V128 V129
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4wj7, PDBe:4wj7, PDBj:4wj7
PDBsum4wj7
PubMed25525273
UniProtQ9BSQ5|CCM2_HUMAN Cerebral cavernous malformations 2 protein (Gene Name=CCM2)

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