Structure of PDB 4wb2 Chain C Binding Site BS01

Receptor Information
>4wb2 Chain C (length=74) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GANLHLLRQKIEEQAAKYKHSVPKKCCYDGARVNFYETCEERVARVTIGP
LCIRAFNECCTIANKIRKESPHKP
Ligand information
>4wb2 Chain E (length=40) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcgaugugguggugcaggguuguugggugucgacgcacgc
<<<.<<<.<<......................>>>>>>>>
Receptor-Ligand Complex Structure
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PDB4wb2 Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H696 S697 V698 K701 Y704 D705 R708 Y712 R721 V722 T723
Binding residue
(residue number reindexed from 1)		H20 S21 V22 K25 Y28 D29 R32 Y36 R45 V46 T47
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006954 inflammatory response
GO:0006956 complement activation
Cellular Component
GO:0005576 extracellular region

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Biological Process
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Cellular Component
External links
PDB RCSB:4wb2, PDBe:4wb2, PDBj:4wb2
PDBsum4wb2
PubMed25901944
UniProtP06684|CO5_MOUSE Complement C5 (Gene Name=C5)

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