Structure of PDB 4um9 Chain C Binding Site BS01

Receptor Information
>4um9 Chain C (length=589) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FNLDVDSPAEYSGPEGSYFGFAVDFFVPSRMFLLVGAPKANTTQPGIVEG
GQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQD
KILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQG
FCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIK
YNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMV
YIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDR
GSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQD
GFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSCPPS
FGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSI
LNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLK
GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPI
TIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4um9 Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
Resolution2.5 Å
Binding residue
(original residue number in PDB)		F177 Y178 D218
Binding residue
(residue number reindexed from 1)		F174 Y175 D215
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4um9, PDBe:4um9, PDBj:4um9
PDBsum4um9
PubMed25383667
UniProtP06756|ITAV_HUMAN Integrin alpha-V (Gene Name=ITGAV)

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